Improving the taste of cannabis spray

AIM:

Complaints about Δ9-tetrahydrocannabinol (THC):cannabidiol (CBD) oromucosal spray (Sativex®; GW Pharma Ltd, Sailsbury, UK) in the management of multiple sclerosis spasticity include unpleasant taste and oral mucosal anomalies. This pilot study assessed the use of sugar-free chewing gum and/or a refrigerated bottle of THC:CBD oromucosal spray to mitigate these effects.

MATERIALS & METHODS:

Patients with multiple sclerosis spasticity (n = 52) at six sites in Italy who were receiving THC:CBD oromucosal spray and had associated oral mucosal effects were randomized into Group A (chewing gum; n = 15); Group B (cold bottle; n = 20); and Group C (cold bottle + chewing gum; n = 17).

RESULTS:

Taste perception in patients receiving chewing gum ± cold bottle intervention (Groups A and C combined) was significantly (p = 0.0001) improved from baseline to week 4 while maintaining spasticity control.

CONCLUSION:

Patient comfort, satisfaction and treatment adherence may benefit from these interventions
This article may be useful to anyone who gets sativex. Sativex is an alcoholic extract of cannabis (i.e a tincture), I thik with a peppermint flavour, so it is like a Creme-de-Menthe spray under the toungue. However, as it is reletively pure alcohol,means that it is going to be a fixative to the inside of the cheek and it is going to taste unpleasant. We know this because in the placebo controlled tirals where people could have 0-20+ puffs of the sativex inhaler and those on placebo where there is no drug to work, should have been puffing away, but they didn't ,and on average had lesss than a half of available. This says the taste isn't good. However, above may be some use if you can get access to treatment

Labels: